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磷酸化Rho GTP酶激活蛋白GAP抗體

產(chǎn)品貨號(hào)：

BN41273R
中文名稱：

磷酸化Rho GTP酶激活蛋白GAP抗體
英文名稱：

Rabbit anti-phospho-RACGAP1 (Ser387) Polyclonal antibody
品牌：

Biorigin

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BN41273R-100ul

100ul

￥2470.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Cow) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱	phospho-RACGAP1 (Ser387)
中文名稱	磷酸化Rho GTP酶激活蛋白GAP抗體
別名	RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387); GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.
產(chǎn)品類型	磷酸化抗體
研究領(lǐng)域	細(xì)胞生物信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子細(xì)胞分化
抗體來(lái)源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, (predicted: Rat, Dog, Cow, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	71kDa
細(xì)胞定位	細(xì)胞核細(xì)胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387:RI(p-S)GC
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases. Subunit: Heterotetramer of two molecules each of RACGAP1 and KIF23. Subcellular Location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Tissue Specificity: Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase. Similarity: Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Rho-GAP domain. SWISS: Q9H0H5 Gene ID: 29127 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.